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Abstract #4991

Multidimensional T1 Relaxation -T2 Relaxation Correlation Spectroscopic Imaging with a Magnetic Resonance Fingerprinting Acquisition

Daeun Kim1, Bo Zhao2,3, Lawrence L. Wald2,3, and Justin P. Haldar1

1Electrical Engineering, University of Southern California, Los Angeles, CA, United States, 2Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 3Harvard Medical School, Boston, MA, United States

T1 Relaxation-T2 Relaxation Correlation Spectroscopic Imaging (RR-CSI) is a novel multidimensional imaging approach that estimates a 2D T1-T2 correlation spectrum at every spatial location, and enables spatial mapping of sub-voxel tissue compartments with very good compartmental resolving capabilities. While RR-CSI was previously demonstrated using data acquired with an inversion recovery multi-echo spin-echo sequence, it can also accommodate data acquired with other encoding schemes. In this work, we investigate an inversion recovery FISP MR fingerprinting acquisition scheme for RR-CSI. Results show, both theoretically and empirically using in vivo human data, that fingerprinting is a viable alternative.

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