Abstract #4991

Multidimensional T1 Relaxation -T2 Relaxation Correlation Spectroscopic Imaging with a Magnetic Resonance Fingerprinting Acquisition

Daeun Kim¹, Bo Zhao^2,3, Lawrence L. Wald^2,3, and Justin P. Haldar¹

¹Electrical Engineering, University of Southern California, Los Angeles, CA, United States, ²Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, United States, ³Harvard Medical School, Boston, MA, United States

T₁ Relaxation-T₂ Relaxation Correlation Spectroscopic Imaging (RR-CSI) is a novel multidimensional imaging approach that estimates a 2D T₁-T₂ correlation spectrum at every spatial location, and enables spatial mapping of sub-voxel tissue compartments with very good compartmental resolving capabilities. While RR-CSI was previously demonstrated using data acquired with an inversion recovery multi-echo spin-echo sequence, it can also accommodate data acquired with other encoding schemes. In this work, we investigate an inversion recovery FISP MR fingerprinting acquisition scheme for RR-CSI. Results show, both theoretically and empirically using in vivo human data, that fingerprinting is a viable alternative.

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