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Abstract #4990

Exploring human cortical microstructure using magnetic resonance fingerprinting at 3T

Irene Wang 1, Rasim Boyacioglu2, Mark A Griswold2, Stephen Jones3, and Dan Ma2

1Epilepsy Center, Cleveland Clinic, Cleveland, OH, United States, 2Radiology, Case Western Reserve University, School of Medicine, Cleveland, OH, United States, 3Imaging Institute, Cleveland Clinic, Cleveland, OH, United States

Human cortical areas are typically differentiated by functions with varying cyto- and myelo- architectures. Since quantitative MR tissue properties, such as T1, T2 and susceptibility, reflect underlying molecular compositions and micro-environment of tissues, multiple quantitative imaging methods have been used to investigate human cortical microstructure at 7T. Here, we used the FSL image analysis tool to process multi-parametric quantitative maps and demonstrated that high resolution multi-parametric maps acquired from a single MR Fingerprinting (MRF) scan at 3T can reveal similar patterns of cyto-architectural information that are typically identified at 7T.

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