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Abstract #5004

Fast 3D Whole-Brain Steady-State CEST at 3T Using MR Multitasking

Pei Han1,2, Zhengwei Zhou2, Anthony Christodoulou2, Sen Ma1,2, Nan Wang1,2, and Debiao Li1,2

1Department of Bioengineering, UCLA, Los Angeles, CA, United States, 2Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States

We propose a fast 3D whole-brain steady-state chemical exchange saturation transfer (CEST) method using MR Multitasking. Exploiting the correlation between images throughout the space, time and frequency dimensions, the low-rank tensor framework shows possibility for further acceleration of steady-state CEST, so that a whole-brain Z-spectrum acquisition can be done within 5 min.

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