Abstract #5004

Fast 3D Whole-Brain Steady-State CEST at 3T Using MR Multitasking

Pei Han^1,2, Zhengwei Zhou², Anthony Christodoulou², Sen Ma^1,2, Nan Wang^1,2, and Debiao Li^1,2

¹Department of Bioengineering, UCLA, Los Angeles, CA, United States, ²Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States

We propose a fast 3D whole-brain steady-state chemical exchange saturation transfer (CEST) method using MR Multitasking. Exploiting the correlation between images throughout the space, time and frequency dimensions, the low-rank tensor framework shows possibility for further acceleration of steady-state CEST, so that a whole-brain Z-spectrum acquisition can be done within 5 min.

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