Abstract #5039

Using D2O As a Diffusible Tracer in Characterizing Tumor Properties on Mice

Pei-Lun Yu¹, Ming Cheng¹, Xiayu Lyu¹, Sheng-Min Huang¹, Kung-Chu Ho², and Fu-Nien Wang¹

¹Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan, ²Division of Nuclear Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan

As a diffusible tracer, D₂O was employed as a negative contrast agent in investigating tumor perfusion in this study. Results show that the transfer constant derived from D₂O perfusion is able to characterize tumor flow properties. Furthermore, we also demonstrated that the initial area under curve of D₂O perfusion has potential in detecting the flow difference between tumor and normal tissue, suggesting the feasibility of semi-quantitative indices for D₂O perfusion.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.