Abstract #0002

Parametric Hemodynamic 4D flow MRI maps for the Characterization of Chronic Thoracic Descending Aortic Dissection

Kelly Jarvis¹, Judith T Pruijssen², Andre Y Son³, Bradley D Allen¹, Gilles Soulat¹, Alireza Vali¹, Alex J Barker⁴, Andrew W Hoel⁵, Mark K Eskandari⁵, S. Chris Malaisrie³, James C Carr¹, Jeremy D Collins⁶, and Michael Markl¹

¹Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ²Department of Radiology and Nuclear Medicine, Radboud University Medical Centre, Nijmegen, Netherlands, ³Division of Cardiac Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ⁴Department of Radiology, University of Colorado, Denver, CO, United States, ⁵Division of Vascular Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ⁶6. Department of Radiology, Mayo Clinic, Rochester, MN, United States

Systematic evaluation of complex flow in descending aortic dissection (DAD) is needed to better understand which patients are predisposed to complications. Our goal was to utilize quantitative maps from 4D flow MRI for monitoring true and false lumen (TL, FL) flow characteristics. 4D flow was acquired in 20 DAD patients (6 medically managed, 14 with surgical repair), and 21 age-matched controls. 4D flow-derived quantitative maps demonstrated global and regional hemodynamic differences between DAD patients and controls. DAD patients with and without repair showed significantly altered TL and FL aortic hemodynamics, indicating this technique’s potential to characterize flow dynamics in DAD.

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