Quantitative pharmacokinetic model parameter maps from dynamic contrast enhanced (DCE)-MRI can provide useful physiologically relevant information about tumor microenvironment, but often in low spatial resolution due to challenges in acquiring high resolution 3D data with high temporal resolution. The purpose of this study is to investigate the feasibility of generating the whole tumor high resolution pharmacokinetic model parameter maps with the 3D-UTE-GRASP1 sequence for both T1 mapping and dynamic scan.
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