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Abstract #0007

Whole tumor pharmacokinetic model analysis with 3D isotropic high resolution using 3D-UTE-GRASP sequence at 7T

Jin Zhang1, Karl Kiser1, Chongda Zhang1, Ayesha Bharadwaj Das1, and Sungheon Gene Kim1
1New York University School of Medicine, New York, NY, United States

Quantitative pharmacokinetic model parameter maps from dynamic contrast enhanced (DCE)-MRI can provide useful physiologically relevant information about tumor microenvironment, but often in low spatial resolution due to challenges in acquiring high resolution 3D data with high temporal resolution. The purpose of this study is to investigate the feasibility of generating the whole tumor high resolution pharmacokinetic model parameter maps with the 3D-UTE-GRASP1 sequence for both T1 mapping and dynamic scan.

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