Meeting Banner
Abstract #0031

Improved accuracy of blood-brain barrier (BBB) assessment with water-extraction-with-phase-contrast-arterial-spin-tagging (WEPCAST) MRI

Zixuan Lin1, Dengrong Jiang1, Yang Li1, Pan Su1, Jay J. Pillai1, and Hanzhang Lu1
1Department of Radiology, Johns Hopkins University, Baltimore, MD, United States

A new scheme of water-extraction-with-phase-contrast-arterial-spin-tagging (WEPCAST) MRI was proposed for non-invasive assessment of blood-brain-barrier (BBB) permeability to water. In this scheme, venous bolus-arrival-time was measured first by Look-Locker WEPCAST and then applied to single-delay long-labeling-duration WEPCAST scan to estimate water extraction fraction. The results showed an improved accuracy for estimation of BBB permeability.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here