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Abstract #0035

Oxygen Extraction Fraction Mapping using Remote Sensing: Spatially Encoded T2-Relaxation-Under-Spin-Tagging (SE-TRUST)

Caitlin O'Brien1, Thomas Okell1, Mark Chiew1, and Peter Jezzard1
1Wellcome Centre for Integrative Neuroimaging (FMRIB), University of Oxford, Oxford, United Kingdom

This work uses remote sensing methods to encode spatial information of venous blood spins in the brain into the longitudinal magnetisation. This information was then decoded remotely from the blood signal in the superior sagittal sinus. A T2-preparation module allowed venous blood T2 and therefore oxygen extraction fraction, to be mapped. An optimum inversion delay (TI) of 2s was found, and the sensitivity of the method to the spatial origins of the blood spins was verified. Low resolution venous T2 maps were obtained in two healthy volunteers. Average values were comparable to global T2 using conventional TRUST.

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