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Abstract #0034

High Resolution Water Exchange Rate Mapping using 3D Diffusion Prepared Arterial Spin Labeled Perfusion MRI

Qihao Zhang1, Thanh D Nguyen2, Jana Ivanidze3, and Yi Wang3
1Cornell University, Ithaca, NY, NY, United States, 2Weill Cornell Medicine College, New York, NY, United States, 3Weill Cornell Medicine, New York, NY, United States

In this work, we propose an optimized acquisition for high resolution water exchange rate (kw) mapping, that uses adiabatic RF pulses, 3D fast spin echo readout, regularized inversion to a direct model of the water exchange rate, and fast T1 mapping. Feasibility and superior performance is shown in a regional based analysis in 6 healthy subjects.

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