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Abstract #0068

Virtual bronchoscopy of neonatal dynamic airway collapse with ultrashort echo-time MRI

Nara S Higano1,2, Alister J Bates1,2,3,4, Erik B Hysinger2,4, Robert J Fleck3,5,6, Andrew D Hahn7, Sean B Fain7,8, Paul S Kingma4,9, and Jason C Woods2,5,6
1Center for Pulmonary Imaging, Cincinnati Children's Hospital, CINCINNATI, OH, United States, 2Pulmonary Medicine, Cincinnati Children's Hospital, CINCINNATI, OH, United States, 3Upper Airway Center, Cincinnati Children's Hospital, CINCINNATI, OH, United States, 4Pediatrics, University of Cincinnati, CINCINNATI, OH, United States, 5Radiology, Cincinnati Children's Hospital, CINCINNATI, OH, United States, 6Pediatrics, University of Cincinnati, Cincinnati, OH, United States, 7Medical Physics, University of Wisconsin - Madison, Madison, WI, United States, 8Radiology, University of Wisconsin - Madison, Madison, WI, United States, 9Neonatology and Pulmonary Biology, Cincinnati Children's Hospital, CINCINNATI, OH, United States

Central airway abnormalities in neonates, e.g. dynamic collapse and stenosis, are serious complications often associated with preterm birth and congenital abnormalities, but have not been extensively studied. These conditions are most often assessed through clinical bronchoscopy, which can be unreliable and poses increased risks to patients. Here, we demonstrate novel visualization of static and dynamic neonatal airway abnormalities on virtual bronchoscopy from high-resolution, retrospectively respiratory-gated ultrashort echo-time MRI, which exhibits good agreement with clinical bronchoscopy. This virtual technique allows for assessment of neonatal airway abnormalities that is readily interpretable to clinicians familiar with clinical bronchoscopy.

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