Abstract #0086

Free-Breathing Volumetric Liver R2* Quantification in Pediatric Patients Using 3D Self-Gating Motion-Compensated Stack-of-Radial MRI

Xiaodong Zhong¹, Houchun H Hu², Tess Armstrong^3,4, Marcel D Nickel⁵, Stephan A.R. Kannengiesser⁵, Vibhas Deshpande⁶, Berthold Kiefer⁵, and Holden H Wu^3,4

¹MR R&D Collaborations, Siemens Healthcare, Los Angeles, CA, United States, ²Department of Radiology, Nationwide Children's Hospital, Columbus, OH, United States, ³Department of Radiological Sciences, University of California Los Angeles, Los Angeles, CA, United States, ⁴Department of Physics and Biology in Medicine, University of California Los Angeles, Los Angeles, CA, United States, ⁵MR Application Predevelopment, Siemens Healthcare GmbH, Erlangen, Germany, ⁶MR R&D Collaborations, Siemens Healthcare, Austin, TX, United States

Liver fat and iron quantification is of growing interest. However, it is challenging and sometimes impossible to perform breath-hold MRI acquisitions in children. Using a breath-hold 3D Cartesian method as reference, a self-gating free-breathing 3D stack-of-radial liver R₂^* quantification technique was evaluated. Results showed that the free-breathing stack-of-radial technique accurately quantified fat even without self-gating, while free-breathing R₂^* quantification had biases caused by respiratory motion and self-gating was necessary for accurate R₂^* quantification in pediatric subjects. This technique has potential for accurate and efficient free-breathing quantification of both liver fat and iron in pediatric patients.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.