Abstract #0154

Eliminating chemical shift and relaxation effects in QSM using SMURF imaging

Beata Bachrata^1,2,3, Bernhard Strasser^1,2,4, Wolfgang Bogner^1,2, Albrecht Ingo Schmid^1,5, Siegfried Trattnig^1,2,3, and Simon Daniel Robinson^1,2,6,7

¹High Field MR Centre, Medical University of Vienna, Vienna, Austria, ²Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ³Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, ⁴Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States, ⁵Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, ⁶Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, ⁷Department of Neurology, Medical University of Graz, Graz, Austria

The accuracy of Quantitative Susceptibility Mapping in fatty regions is adversely affected by the chemical shift effects and by the relaxation rate differences between fat and water. We propose using a recently developed water-fat separation technique based on multi-band principles, Simultaneous Multiple Resonance Frequency (SMURF) imaging, to correct for these effects. SMURF achieves clean water-fat separation in the head-and-neck, allowing the generation of recombined water-fat images fully corrected for chemical shift and relaxation effects. This makes bias-free Quantitative Susceptibility Mapping possible in body regions containing significant amounts of fat, with the free selection of echo-times, receiver bandwidths and flip angles.

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