Prematurity-related injuries often result in aberrant brain maturation, specifically on peri-thalamic white matter. We investigated the effects of these injuries on the intra-thalamic tissue integrity and on thalamocortical connectivity. We found that injuries did not substantially affect thalamic volume or thalamic DTI parameters, but did have a substantial effect on the correlative growth between the thalamus and cortex. This implies that brain injuries disrupt the reciprocal development of the thalamus and cortex, which may indicate abnormal thalamocortical connectivity.
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