We used multi-shell diffusion imaging to investigate differences in the visual pathways of children undergoing epilepsy surgery and demonstrated its potential for clinical practice. In particular, we compared the traditional Diffusion Tensor Imaging model with the Spherical Mean Technique model and evaluated its potential to produce measures of tissue microstructure not confounded by orientation effects in both a healthy and patient population. Furthermore, we explored the effect of brain surgery and applied Constrained Spherical Deconvolution derived tractography to determine the frequency and influence of the extent and location of resection on the integrity of the visual system after the operation.
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