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Abstract #0262

Accelerated T2 Mapping of the Lumbar Intervertebral Discs: Robust Quantification in Clinically Feasible Acquisition Times

Marcus Raudner1, Markus Schreiner1,2, Tom Hilbert3,4,5, Tobias Kober3,5,6, Anna Szelenyi7, Vladimir Juras1, and Siegfried Trattnig1
1High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2Department of Orthopedics and Trauma Srugery, Medical University of Vienna, Vienna, Austria, 3Advanced Clinical Imaging Technology, Siemens Healthcare, Lausanne, Switzerland, 4Department of Radiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland, 5LTS5, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland, 6Department of Radiology, University Hospital and University of Lausanne, Lausanne, Switzerland, 7Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria

The physiological biochemical state of the intervertebral disc (IVD) allows for passive water-storing capabilities because of a high concentration of glycosaminoglycans (GAG) and an inherent structural integrity. T2 mapping can quantitatively assess the IVD’s water content and GAG concentration, but a typical 2D multi echo spin echo (MESE) sequence suffers from clinically prohibitive scan times. To resolve this, we compared the MESE sequence against GRAPPATINI, an accelerated sequence combining parallel imaging and a model-based reconstruction for T2 quantification which uses undersampling to shorten the scan time from 13:18 to 2:27 minutes.

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