Simultaneous stiffness assessment of multiple organs in patients with systemic diseases may be beneficial. Here we used four passive MRE drivers to assess the feasibility and repeatability of simultaneous stiffness measurements of the liver, spleen and kidneys using 60-Hz vibrations. No significant bias was observed in the stiffness measurements of the liver and kidneys with 1 versus multiple drivers. Splenic stiffness was lower with four drivers. With four drivers, it is possible to obtain simultaneous stiffness measurements of the liver, spleen and kidneys with repeatability coefficients similar to those using a single driver while also overcoming attenuation in the liver.
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