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Abstract #0331

Preoperative prediction of HCC with highly aggressive characteristics using quantitative parameters derived from hepatobiliary phase

Zheng Ye1, Yi Wei1, Jie Chen1, and Bin Song1
1West China Hospital, Sichuan University, Chengdu, China

Hepatocellular carcinoma (HCC) with highly aggressive characteristics is usually actively proliferated and easily relapse, thereby requiring adjuvant therapies before surgery, like preoperative TACE, to improve the patients’ prognosis. Ki-67 labeling index (LI) was reported to be highly correlated with aggressive propensity of HCC, and thus could affect the treatment response of the tumor and prognosis directly. Although most of HCC presented hypointensity on hepatobiliary phase (HBP), the absolute signal intensity and relative contrast enhancement ratio are not the same. In this study, we prospectively investigate the usefulness of HBP quantitative parameters for preoperative prediction of aggressiveness in HCC patients.

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