Abstract #0336

A study of sensitivity of quantitative MRI measurements to the presence of iron in the liver

Yurui Qian¹, Jian Hou¹, Yixiang Wang¹, Vincent Wong², Queenie Chan³, Weibo Chen⁴, Min Deng¹, Franklin Au¹, Anthony Chan⁵, Winnie Chu¹, and Weitian Chen¹

¹Department of Imaging and Interventional Radiology, Chinese University of Hong Kong, Hong Kong, Hong Kong, ²Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong, Hong Kong, ³Philips Healthcare, Hong Kong, Hong Kong, ⁴Philips Healthcare, Shanghai, China, ⁵Department of Anatomical and Cellular Pathology, Chinese University of Hong Kong, Hong Kong, Hong Kong

MRI is widely used as a non-invasive method to diagnose and monitor liver diseases. For certain quantitative MRI techniques, liver iron content may affect the measurement. In this work, we investigated the influence of liver iron content on several quantitative MRI methods, including macromolecular proton fraction, T1rho and intravoxel incoherent motion.

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