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Abstract #0336

A study of sensitivity of quantitative MRI measurements to the presence of iron in the liver

Yurui Qian1, Jian Hou1, Yixiang Wang1, Vincent Wong2, Queenie Chan3, Weibo Chen4, Min Deng1, Franklin Au1, Anthony Chan5, Winnie Chu1, and Weitian Chen1
1Department of Imaging and Interventional Radiology, Chinese University of Hong Kong, Hong Kong, Hong Kong, 2Department of Medicine & Therapeutics, Chinese University of Hong Kong, Hong Kong, Hong Kong, 3Philips Healthcare, Hong Kong, Hong Kong, 4Philips Healthcare, Shanghai, China, 5Department of Anatomical and Cellular Pathology, Chinese University of Hong Kong, Hong Kong, Hong Kong

MRI is widely used as a non-invasive method to diagnose and monitor liver diseases. For certain quantitative MRI techniques, liver iron content may affect the measurement. In this work, we investigated the influence of liver iron content on several quantitative MRI methods, including macromolecular proton fraction, T1rho and intravoxel incoherent motion.

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