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Abstract #0338

Evaluation of liver function by using Hepatocyte fraction of Gd-EOB-DTPA-Enhanced MRI based on MELD score

Mao-Tong LIU1, Xue-Qin ZHANG1, Jian LU1, and Wei-Bo CHEN2
1Third Affiliated Hospital of Nantong University & Nantong Third People's Hospital, Nan Tong, China, 2Philips Healthcare Shanghai, China, Shang Hai, China

The purpose of this study was to identify whether hepatocyte fraction that based on Gadoxetic Acid–enhanced MRI is useful for the assessment of liver function. Firstly, T1 mapping imaging was performed before and 20 minutes after Gd-EOB-DTPA administration, The following parameters are then obtained from the images: pre- and postcontrast T1 values of the liver (T1pre and T1post), increase in the T1 relaxation rate (Δ R1), rate of the decrease of the T1 relaxation time (Δ T1), hepatocyte fraction (HeF), and uptake coefficient (K). Our study showed that hepatocyte fraction can be used to evaluate the liver function of patients with hepatitis B cirrhosis, K value has high diagnostic efficiency.

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