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Abstract #0358

Feasibility of dynamic DTI exercise response and resistance dependence in quadriceps muscle

Eric E. Sigmund1, Steven H. Baete1, and Danielle Costanzo1
1Radiology, NYU Langone Health, New York, NY, United States

We describe measurement of resistance dependence diffusion metric exercise response in thigh muscle with a multiple echo diffusion tensor imaging (MEDITI) on a clinical 3 T scanner. With radial imaging, accelerated diffusion encoding, and compressed sensing reconstruction, spatial resolution of 3.4 mm and temporal resolution of 16 s was achieved. Using an MR-compatible ergometer with pneumatic resistance and force/displacement monitoring, post-exercise recovery of DTI metrics in the rectus femoris following quadriceps extension was monitored as a function of resistance. Significant dependences of response on resistance were observed.

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