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Abstract #0365

Intra-session and inter-subject variability of 3D-FID-MRSI using single-echo volumetric EPI navigators at 3T

Philipp Moser1, Korbinian Eckstein1, Lukas Hingerl1, Michael Weber1, Stanislav Motyka1, Bernhard Strasser1,2, Andre van der Kouwe3, Simon Robinson1, Siegfried Trattnig1,4, and Wolfgang Bogner1
1High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Harvard Medical School, Massachusetts General Hospital, Vienna, MA, United States, 3Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology,, Harvard Medical School, Massachusetts General Hospital, Boston, MA, United States, 4Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

We demonstrate the combination of 3D free induction decay proton MR spectroscopic imaging and spatial encoding via concentric-ring trajectories at 3T. To improve the reliability a well as the temporal stability, single-echo, imaging-based volumetric navigators for real-time motion/shim-correction were additionally integrated. All intra-subject coefficients of variation and most of the inter-subject coefficients of variation obtained with motion/shim-correction were lower (i.e., better) than without and resulted in higher SNRs and lower CRLBs.

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