Meeting Banner
Abstract #0385

MRSI of the prostate revisited: The potential role of GOIA-sLASER in multiparametric MRI of central gland prostate cancer

Neda Gholizadeh1, Peter B Greer2,3, John Simpson2,3, Jonathan Goodwin2,3, Peter Lau4,5, Arend Heerschap6, and Saadallah Ramadan1,5
1Health Science, The University of Newcastle, Newcastle, Australia, 2Radiation Oncology, Calvary Mater Newcastle, Newcastle, Australia, 3Physics and mathematics, The University of Newcastle, Newcastle, Australia, 4Radiology, Calvary Mater Newcastle, Newcastle, Australia, 5Imaging Centre, Hunter Medical Research Institute (HMRI), Newcastle, Australia, 6Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, Nijmegen, Netherlands

Due to histological heterogeneity of the central gland, accurate detection of central gland prostate cancer remains a challenge. A reliable and non-invasive imaging technique could increase the sensitivity and specificity for identification of central gland lesions missed by PI-RADS V2 or biopsies. This study evaluates the diagnostic performance of individual and combined parameters of an mp-MRI exam, employed for PI-RADS evaluations (T2WI, DWI, DCE) and advanced GOIA-sLASER MRSI using an external phased-array coil for central gland prostate cancer detection, localization and grading. The results demonstrate that MRSI using GOIA-sLASER considerably improves central gland prostate cancer detection and localization.

This abstract and the presentation materials are available to 2020 meeting attendees and eLibrary customers only; a login is required.

Join Here