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Abstract #0439

3D-SBCSI Xenon-129 lung MRI: Comparison of Healthy, CF, IPF, and COPD Subjects

Vicki Huang1, Steven Guan1, Nick Tustison1, Kun Qing1, Yun Shim2, John Mugler1, Talissa Altes3, Dana Albon2, Deborah Froh2, Borna Mehrad4, James Patrie5, Allan Ropp1, Lucy Gettle2, Mu He1, and Jaime Mata1
1Radiology & Medical Imaging, University of Virginia, Charlottesville, VA, United States, 2Medicine, University of Virginia, Charlottesville, VA, United States, 3Radiology, University of Missouri, Columbia, MO, United States, 4University of Florida, Gainesville, FL, United States, 5Public Health, University of Virginia, Charlottesville, VA, United States

The results of this study indicated that hyperpolarized Xe-129 MR 3D-SBCSI is sensitive to physiology of lung diseases and can therefore be used to differentiate lung disease and monitor disease progression on regional level and characterizing disease phenotypes and co-morbidities in the future.

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