Abstract #0439

3D-SBCSI Xenon-129 lung MRI: Comparison of Healthy, CF, IPF, and COPD Subjects

Vicki Huang¹, Steven Guan¹, Nick Tustison¹, Kun Qing¹, Yun Shim², John Mugler¹, Talissa Altes³, Dana Albon², Deborah Froh², Borna Mehrad⁴, James Patrie⁵, Allan Ropp¹, Lucy Gettle², Mu He¹, and Jaime Mata¹

¹Radiology & Medical Imaging, University of Virginia, Charlottesville, VA, United States, ²Medicine, University of Virginia, Charlottesville, VA, United States, ³Radiology, University of Missouri, Columbia, MO, United States, ⁴University of Florida, Gainesville, FL, United States, ⁵Public Health, University of Virginia, Charlottesville, VA, United States

The results of this study indicated that hyperpolarized Xe-129 MR 3D-SBCSI is sensitive to physiology of lung diseases and can therefore be used to differentiate lung disease and monitor disease progression on regional level and characterizing disease phenotypes and co-morbidities in the future.

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