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Abstract #0519

A non-local filtering based approach for high quality quantitative susceptibility mapping reconstruction

Srikant Kamesh Iyer1, Brianna F Moon2, Nicholas J Josselyn1, Eileen Hwuang2, Jeffrey B Ware1, David Roalf3, Jae W Song1, S. Ali Nabavizadeh1, and Walter R Witschey1
1Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, 2Bioengineering, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States, 3Psychiatry, University of Pennsylvania, Philadelphia, PA, United States

This abstract presents a novel non-local filtering based reconstruction approach for high quality quantitative susceptibility mapping (QSM). Popular QSM techniques that use fixed sparsity priors such as total variation or total generalized variation often suffer from blurring of fine features (e.g. edges). Since QSM images have non-local spatial redundancies in the form of self-similarity, we develop an approach that uses non-local grouping by 4D cube-matching and collaborative filtering in a plug-and-play (PnP) alternating direction method of multiplier (ADMM) framework. We show that the proposed non-local filtering based reconstruction approach achieves sharper edges and better preservation of fine features.

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