Abstract #0541

Short-term effects of transcranial direct current stimulation (tDCS) on cerebral blood flow measured with ASL MRI

Iris Asllani^1,2, Francesco Di Lorenzo³, Katerina Gialopsou³, Joseph G Woods^4,5, Marco Bozzali³, and Mara Cercignani³

¹Neuroscience, University of Sussex, Brighton, United Kingdom, ²Biomedical Engineering, Rochester Institute of Technologygy, Rochester, NY, United States, ³University of Sussex, Brighton, United Kingdom, ⁴Radiology, University of California San Diego, San Diego, CA, United States, ⁵University of Oxford, Oxford, United Kingdom

Short-term effects of transcranial direct current stimulation (tDCS) on CBF were measured using arterial spin labeling (ASL) MRI. Results showed that anodal surface stimulation of the motor region was followed by an increase in gray matter CBF in that region. Conversely, CBF in the stimulated region following a cathodal stimulation decreased. There was no effect of sham stimulation on the CBF of the stimulated area. These findings may help forge a new path toward a better understanding of the neuro-physiological effects of tDCS in humans.

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