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Abstract #0541

Short-term effects of transcranial direct current stimulation (tDCS) on cerebral blood flow measured with ASL MRI 

Iris Asllani1,2, Francesco Di Lorenzo3, Katerina Gialopsou3, Joseph G Woods4,5, Marco Bozzali3, and Mara Cercignani3
1Neuroscience, University of Sussex, Brighton, United Kingdom, 2Biomedical Engineering, Rochester Institute of Technologygy, Rochester, NY, United States, 3University of Sussex, Brighton, United Kingdom, 4Radiology, University of California San Diego, San Diego, CA, United States, 5University of Oxford, Oxford, United Kingdom

Short-term effects of transcranial direct current stimulation (tDCS) on CBF were measured using arterial spin labeling (ASL) MRI. Results showed that anodal surface stimulation of the motor region was followed by an increase in gray matter CBF in that region. Conversely, CBF in the stimulated region following a cathodal stimulation decreased. There was no effect of sham stimulation on the CBF of the stimulated area. These findings may help forge a new path toward a better understanding of the neuro-physiological effects of tDCS in humans.

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