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Abstract #0540

Real-Time EPI Phase Contrast Acquisition for Imaging of CSF Dynamics

Petrice Mostardi Cogswell1, Sandeep K Ganji2, Daniel D Borup1, Jeffrey L Gunter1, John Huston III1, and Clifford R Jack Jr1
1Radiology, Mayo Clinic, Rochester, MN, United States, 2Philips Healthcare, Gainesville, FL, United States

CSF flow has been most commonly evaluated using a gated 2D phase contrast (PC) acquisition at the cerebral aqueduct or foramen magnum. However, real-time acquisitions that allow for evaluation of changes in flow with the cardiac and respiratory may provide additional insight into CSF dynamics disorders. In this study we apply a real-time EPI based PC acquisition for imaging of intracranial CSF flow at multiple intracranial locations. Quantitative analyses are validated by comparison with a standard phase contrast acquisition. Frequency spectra analysis demonstrates dominant variations in CSF flow with the cardiac and respiratory cycles.

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