Measurement of quantitative, tissue-specific MR properties such as water content or relaxation times using quantitative-MRI at clinical field strength is a well-explored topic. However, none of the commonly used standard brain atlases, e.g., MNI or JHU, provide quantitative information. Utilising the framework of quantitative-MRI of the brain, this work reports on the development of the first quantitative in-vivo water content atlas based on twenty healthy volunteers datasets. Additionally, water content maps from patients with pathological changes in the brain were compared voxel-wise. These results suggest that quantitative-MRI in combination with water content atlas allows careful and quantitative interpretation of disease.
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