MR-STAT is a recently developed technique which aims at reconstructing multi-parametric quantitative maps (T1, T2, PD, etc.) from a short cartesian acquisition. Previous research efforts have focused on the feasibility of the MR-STAT framework from a technical point of view. In this work, we present the implementation of a five-minute long high-resolution whole-brain MR-STAT protocol in a clinical trial and show the first results obtained from nine subjects. Synthetically generated contrast images as well as quantitative parametric maps show the robustness and the practical feasibility of the 5 minute long comprehensive MR-STAT protocol.