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Abstract #0559

Accelerated 3D multiparametric MRI in glioma patients - Initial clinical experience

Carolin M Pirkl1,2, Laura Nuñez-Gonzalez3, Pedro A Gómez1, Sebastian Endt1,2, Rolf F Schulte2, Guido Buonincontri4,5, Marion Smits3, Bjoern H Menze1, Marion I Menzel2,6, and Juan A Hernandez-Tamames3
1Informatics, Technical University of Munich, Munich, Germany, 2GE Healthcare, Munich, Germany, 3Radiology & Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, Netherlands, 4Fondazione Imago7, Pisa, Italy, 5IRCCS Fondazione Stella Maris, Pisa, Italy, 6Physics, Technical University of Munich, Munich, Germany

In brain tumor diagnosis, fully quantitative, multiparametric MRI offers great opportunities as it allows for comprehensive tissue and hence tumor characterization which is essential for treatment planning and monitoring the treatment response. With its highly accelerated acquisition, advanced rapid MR mapping techniques facilitate multiparametric imaging in clinically acceptable scan times, providing quantitative, reproducible and accurate diagnostic information that is less affected by system and interpretation biases. In this work, we present initial clinical results and demonstrate the feasibility of a novel 3D multiparametric quantitative transient-state imaging (QTI) acquisition scheme in glioma patients.

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