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Abstract #0568

The Utility of Amide Proton Transfer-weighted Imaging and  Diffusion Kurtosis Imaging in the Diagnosis of Benign and Malignant Breast Lesions

Nan Meng1, Xuejia Wang2, Dongming Han2, Jing Sun3, Wenling Liu2, Kaiyu Wang4, and Meiyun Wang*5
1Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China, 2Department of MRI, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China, 3Department of Pediatrics, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, China, 4GE Healthcare, MR Research China, Beijing, China, 5Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou, China

Amide proton transfer-weighted imaging (APTWI) has unique advantages in displaying the metabolism of diseased proteins. Diffusion kurtosis imaging (DKI) can quantify the diffusion state water molecules in tissues with a non-gaussian model, thus correcting the deviation of the DWI model and improving the detection of lesions. Our results show that compared with APTWI, the DKI is more effective in the diagnosis of benign and malignant breast tumors.

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