Pre-eclampsia (PE) is one of the most common, yet serious, complications of pregnancy. Its manifestations during pregnancy -high blood pressure, proteinuria and placental lesions- are associated with both maternal and fetal morbidity and mortality. Maternal symptoms resolve after delivery but a lifelong elevated risk for cardiovascular disease (CVD) remains. The CARP study combines functional placental and fetal MRI with (maternal) cardiovascular MR during pregnancy at the time of maximal stress to the maternal heart, in an attempt to disentangle the complex cardiac and placental interactions in disease etiology and to predict maternal cardiovascular risk in later life.
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