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Abstract #0577

Quantitative Perfusion Measurements of the Human Placenta with FAIR and pCASL Arterial Spin Labeling at 3T: Initial Feasibility

Quyen N. Do1, Christina Herrera2, Matthew A. Lewis1, Yin Xi1,3, Catherine Y. Spong2, Diane M. Twickler1,2, and Ananth J. Madhuranthakam1,4
1Radiology, UT Southwestern Medical Center, Dallas, TX, United States, 2Obstetrics and Gynecology, UT Southwestern Medical Center, Dallas, TX, United States, 3Population and Data Sciences, UT Southwestern Medical Center, Dallas, TX, United States, 4Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States

Quantitative measurement of placental perfusion is important for the assessment of placental function. We have developed and optimized a non-contrast perfusion MR imaging technique utilizing pseudo-continuous arterial spin labeling (pCASL) to quantitatively measure human placental perfusion at 3T. Placental perfusion was also assessed using flow-sensitive alternating inversion recovery (FAIR). The average placental blood flow (108±47 mL/100g/min) was comparable to published literature values.

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