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Abstract #0583

Placenta Accreta Spectrum (PAS) Disorders Investigated with Multi-Compartment Placental MRI

Nada Mufti1,2, Patrick O'Brien3, George Attilakos3, Magdalena Sokolska4, Priya Narayanan3, Rosalind Aughwane1, Neil Sebire5, Imen Ben-Salha3, Nafisa Wilkinson3, Giles Kendall1,3, Jan Deprest1,3,6, David Atkinson7, Tom Vercauteren2,6, Sebastien Ourselin2, Anna L David1,3,6, and Andrew Melbourne2,8
1Institute for Women's Health, University College London (UCL), London, United Kingdom, 2School of Biomedical Engineering and Imaging Sciences (BMEIS), Kings College London, London, United Kingdom, 3University College London Hospital, London, United Kingdom, 4Department of Medical Physics and Biomedical Engineering, University College London Hospital (UCLH), London, United Kingdom, 5Great Ormond Street Hospital for Children, London, United Kingdom, 6University Hospitals, KU Leuven, Leuven, Belgium, 7Centre for Medical Imaging (CMI), University College London (UCL), London, United Kingdom, 8Department of Medical Physics and Biomedical Engineering, University College London (UCL), London, United Kingdom

Uterine scarring from caesarean section (CS) can lead to subsequent abnormally adherent or invasive placenta. Failure to recognise Placenta Accreta Spectrum disorders prior to delivery can potentially cause catastrophic bleeding and death. Complex surgical interventions may be required to remove placental invasion of the uterine myometrium and nearby organs. Antenatal detection and correct PAS grading are important to plan delivery. Current ultrasound and MRI imaging are limited to subjective assessment of vascular invasion. We propose a multi-compartment model1 that can quantify vascularity and proportion of abnormal placentation across the previous CS scar for objective diagnosis and to assist surgical planning.

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