Abstract #0590

Comparative Analysis of the Value of APTWI and DKI in Evaluating the Histological Features of Uterus Cervical Cancer

Nan Meng¹, Xuejia Wang², Dongming Han², Xiaoyue Ma¹, Yan Bai³, Kaiyu Wang⁴, and Meiyun Wang*³

¹Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China, ²Department of MRI, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China, ³Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou, China, ⁴GE Healthcare, MR Research China, Beijing, China

Amide proton transfer-weighted imaging (APTWI) has unique advantages in displaying the metabolism of diseased proteins. Diffusion kurtosis imaging (DKI) can quantify the diffusion state water molecules in tissues with a non-gaussian model, thus correcting the deviation of the DWI model and improving the detection of lesions. Our results show that compared with APTWI, the DKI is more effective in evaluating the pathological and physiological characteristics of uterus cervical cancer (UCC).

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