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Abstract #0648

Impact of cerebrospinal and blood flow pulsatilities on periventricular white matter in patients with hydrocephalus

Fadoua Saadani-Makki1,2,3, Malek Makki3, Serge Metanbou4, Cyrille Capel 5, and Olivier Bal├ędent1,2
1Department of Image Processing, University Hospital, Amiens, France, 2CHIMERE EA 7516, Research Team for Head & Neck, University of Picardie Jules Verne, Amiens, France, 3GIE Faire Face, CHU Amiens Picardie, Amiens, France, 4Department of Radiology, University Hospital, Amiens, France, 5Department of Neurosurgery, University Hospital, Amiens, France

The aim of this study was to assess the relationship between neuro-fluids dynamic and microstructure architecture of white matter fibers in hydrocephalus patients. Twenty-eight hydrocephalus patients underwent simultaneously diffusion tensor and phase contrast imaging. A statistical correlation between diffusion and flow parameters has shown a biological causal relationship between abnormal brain neuro-fluids dynamic and white matter alterations in hydrocephalus patients.

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