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Abstract #0663

Multiple phase unwrapping of 4D-flow MRI in cardiovascular valves and vessels

Joao Filipe Fernandes1, Alessandro Faraci1, Marzia Rigolli2, Umar Shehzad1, Saul Myerson2, David Nordsletten1,3, and Pablo Lamata1
1School of Biomedical Engineering & Imaging Sciences, King's College London, London, United Kingdom, 2Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom, 3Department of Surgery and Biomedical Engineering, University of Michigan, Ann Arbor, MI, United States

Accurate quantification of both high and low blood velocities is important for clinical decision-making in cardiovascular conditions like aortic valve stenosis. Multi-VENC acquisition is a potential solution. An alternative, without increasing acquisition time, is enabled here by correcting 4D-Flow MRI multi-aliasing along tubular structures. Our solution is based on continuity principles in successive cross-section planes, outperforming the state-of-the-art Laplacian-based solution which only performs single-wrap corrections. The accuracy of proposed method is verified in 4D-Flow MRI of 25 aortic stenotis patients with VENC of 1m/s, where double and triple unwrapping were needed to match velocity values measured by Doppler echocardiography.

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