Meeting Banner
Abstract #0693

Transportable hyperpolarized glucose samples: towards remote dissolution DNP

Andrea Capozzi1,2, Jan Kilund1, Magnus Karlsson1, Mathilde Hauge Lerche1, and Jan Henrik Ardenkjaer-Larsen1
1Health Technology, Danish Technical University, Kongens Lyngby, Denmark, 2IPHYS, EPFL, Lausanne, Switzerland

Our vision is to enable delivery of hyperpolarized compounds to MR-facilities that currently have no access to hyperpolarization technology. Today this is not the case and represents a main shortcoming of hyperpolarized-MR via dissolution Dynamic Nuclear Polarization (dDNP). The cause is the presence, in the dDNP sample, of organic free radicals necessary to generate the hyperpolarization. We herein present a paradigm shift in the technique built on the employment of photo-induced thermally-labile free radicals. We demonstrate quenching of the paramagnetic species while preserving most of the polarization in the case of hyperpolarized glucose.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.

Keywords