Conventional wisdom suggests that it is necessary to average the diffusion signal over the gradient directions to map microstructural features in the presence of orientational heterogeneity. Contrary to this belief, we show that powder-averaging the signal is redundant and leverage this insight to perform, within the same scan time, diffusion experiments with many rather than few b-values and with many rather than few gradient waveforms for b-tensor encoding and beyond, facilitating the translation of advanced techniques such as microscopic diffusion spectrum imaging to clinical practice.
This abstract and the presentation materials are available to members only; a login is required.