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Abstract #0790

Reproducibility, Repeatability and Preliminary Clinical Results of Free-Breathing Isotropic 3D Whole-Heart T2 Mapping

Aurelien Bustin1, Alina Hua1, Giorgia Milotta1, Olivier Jaubert1, Reza Hajhosseiny1, Tevfik Ismail1, René Botnar1, and Claudia Prieto1
1Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Myocardial T2 mapping has emerged as a promising tool for edema characterization and detection of myocardial inflammation. T2 mapping is conventionally performed under breath-hold by acquiring multiple T2-prepared images using 2D bSSFP. However, 2D imaging and breath-holding impedes high spatial resolution, limits whole-heart coverage and can be challenging in some patients. We developed a free-breathing 3D whole-heart T2 mapping framework that achieves high isotropic resolution in a clinically feasible scan time in healthy subjects. Here we sought to quantify the reproducibility and repeatability of this technique and assess its performance to detect myocardial inflammation in a clinical setting.

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