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Abstract #0890

T2-BUDA-gSlider: fast T2 mapping with blip-up/down acquisition, generalized SLIce Dithered Enhanced Resolution and subspace reconstruction

Xiaozhi Cao1,2,3, Congyu Liao2,3, Zijing Zhang2,4, Siddharth Srinivasan Iyer2,5, Hongjian He1, Kawin Setsompop2,3,6, Jianhui Zhong1, and Berkin Bilgic2,3,6
1Center for Brain Imaging Science and Technology, Department of Biomedical Engineering, Zhejiang University, Hangzhou, China, 2Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, charlestown, MA, United States, 3Department of Radiology, Harvard Medical School, charlestown, MA, United States, 4State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou, China, 5Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 6Harvard-MIT Department of Health Sciences and Technology, Cambridge, MA, United States

We propose to combine the gSlider acquisition and blip-up/down acquisition (BUDA) to achieve high-resolution and distortion-free T2 mapping. Firstly, we incorporate Hankel structured low-rank constraint into BUDA reconstruction to recover distortion-free images from blip-up/down shots without navigation. To utilize the similarity among RF-encodings and TEs, we introduce a model-based shuffling-gSlider joint reconstruction to recover high-resolution thin-slice images by gradually eliminating the weak coefficient components during the iterative reconstruction. Finally, the reconstructed images are used to obtain quantitative T2 maps. The proposed method enables distortion-free high-quality whole-brain T2 mapping with 1 mm isotropic resolution within ~1 minute.

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