Abstract #0890

T2-BUDA-gSlider: fast T2 mapping with blip-up/down acquisition, generalized SLIce Dithered Enhanced Resolution and subspace reconstruction

Xiaozhi Cao^1,2,3, Congyu Liao^2,3, Zijing Zhang^2,4, Siddharth Srinivasan Iyer^2,5, Hongjian He¹, Kawin Setsompop^2,3,6, Jianhui Zhong¹, and Berkin Bilgic^2,3,6

¹Center for Brain Imaging Science and Technology, Department of Biomedical Engineering, Zhejiang University, Hangzhou, China, ²Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, charlestown, MA, United States, ³Department of Radiology, Harvard Medical School, charlestown, MA, United States, ⁴State Key Laboratory of Modern Optical Instrumentation, College of Optical Science and Engineering, Zhejiang University, Hangzhou, China, ⁵Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, ⁶Harvard-MIT Department of Health Sciences and Technology, Cambridge, MA, United States

We propose to combine the gSlider acquisition and blip-up/down acquisition (BUDA) to achieve high-resolution and distortion-free T₂ mapping. Firstly, we incorporate Hankel structured low-rank constraint into BUDA reconstruction to recover distortion-free images from blip-up/down shots without navigation. To utilize the similarity among RF-encodings and TEs, we introduce a model-based shuffling-gSlider joint reconstruction to recover high-resolution thin-slice images by gradually eliminating the weak coefficient components during the iterative reconstruction. Finally, the reconstructed images are used to obtain quantitative T₂ maps. The proposed method enables distortion-free high-quality whole-brain T₂ mapping with 1 mm isotropic resolution within ~1 minute.

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