Spatial misencoding of the vascular signal due to flow is an imaging artifact that presents a significant challenge for in vivo MRI at high resolutions (≤0.5mm). Here we propose a method for mitigating this artifact in multi-echo gradient recalled echo (ME-GRE) images at 350μm isotropic resolution by applying 90° rotations to their phase-encoding direction. After applying our method, we demonstrate clearly visible stria of Gennari, intracortical veins, and pial vessels while mitigating the flow artifact. In addition, we report T2* estimates of several human brain tissues (artery, vein, gray/white matter, CSF) in-vivo which are valuable for future hemodynamic signal modeling.
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