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Abstract #0921

Quantitative 23Na MRI of mild traumatic brain injury: Initial findings

Teresa Gerhalter1, Rosemary Peralta1, Mickael Tordjman1, Julia Zabludovsky1, Seena Dehkharghani1, Alejandro Zarate2, Soo-Min Shin3, Ilya Aylyarov3, Tamara Bushnick2, Jonathan M. Silver4, Stephen P. Wall3, Brian S. Im2, Ryan Brown1, Guillaume Madelin1, and Ivan I. Kirov1
1Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 2Department of Rehabilitation Medicine, New York University School of Medicine, New York, NY, United States, 3Ronald O. Perelman Department of Emergency Medicine, New York University School of Medicine, New York, NY, United States, 4Department of Psychiatry, New York University School of Medicine, New York, NY, United States

In this quantitative sodium MRI study, 24 mild traumatic brain injury (mTBI) and 9 controls were scanned at 3 T. Total sodium content (TSC) was calculated in five different subcortical regions, as well as in global grey and white matter. TSC in mTBI did not differ statistically from controls for the examined regions. Patients with findings on conventional 1H imaging (e.g. lesions, microhemorrhages) did not differ from patients without such findings in their TSC. More patients and controls are being recruited to strengthen the statistical power of these comparisons.

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