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Abstract #0974

Simultaneous distortion and motion correction in abdominal DW-MRI using dual echo EPI and slice-to-volume registration

Jaume Coll-Font1,2, Onur Afacan1,2, Scott Hoge2,3, Bahram Marami4, Ali Gholipour1,2, Jeanne Chow1,2, Simon Warfield1,2, and Sila Kurugol1,2
1Radiology, Boston Children's Hospital, Boston, MA, United States, 2Harvard Medical School, Boston, MA, United States, 3Radiology, Brigham and Women's Hospital, Boston, MA, United States, 4Icahn School of Medicine at Mount Sinai, New York, NY, United States

Diffusion-weighted MRI (DW-MRI) has been increasingly used in abdominal applications. However, unavoidable respiratory motion, as well as B0 field inhomogeneities reduce the accuracy of the quantitative parameters and hinders clinical applicability. In this work, we present a dual echo EPI DW-MRI and slice-to-volume registration method to jointly correct for geometric distortion and motion of the kidneys. The results show that our method effectively reduced geometric distortions, improved alignment of the DW-MR volumes and increased the precision of the estimated quantitative parameters.

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