Meeting Banner
Abstract #0978

Distortion-free, submillimeter-isotropic-resolution diffusion MRI with gSlider BUDA-EPI and multi-coil dynamic B0 shimming

Congyu Liao1, Berkin Bilgic1, Qiyuan Tian1, Jason Stockmann1, Qiuyun Fan1, Siddharth Srinivasan Iyer1,2, Fuyixue Wang1,3, Chanon Ngamsombat1,4, Xiaozhi Cao1, Mary Kate Manhard1, Susie Y. Huang1, Lawrence L. Wald1, and Kawin Setsompop1
1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States, 2Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 3Harvard-MIT Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States, 4Department of Radiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Thailand

Diffusion magnetic resonance imaging (dMRI) is a highly sensitive imaging modality, but is limited in spatial resolution and signal-to-noise ratio (SNR). In this work, we combine an SNR-efficient acquisition and model-based reconstruction strategies with newly-available hardware instrumentation to achieve distortion-free in-vivo dMRI at 600-860 ┬Ám isotropic voxel size with high fidelity and sensitivity on a clinical 3T scanner. At this resolution, it is possible to accurately probe the microstructure of different cortical layers in the human brain.

This abstract and the presentation materials are available to members only; a login is required.

Join Here