Abstract #0986

Sliding-Slab Profile Encoding (SLIPEN) for Eliminating Slab Boundary Artifact in Three-Dimensional Multi-slab Diffusion-Tensor Imaging

Xiaoxi Liu^1,2, Di Cui¹, Xucheng Zhu², Edward S. Hui^1,3, Queenie Chan⁴, Peder E.Z. Larson², and Hing-Chiu Chang¹

¹Department of Diagnostic Radiology, The University of Hong Kong, Hong Kong, China, ²Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, United States, ³The State Key Laboratory of Brain and Cognitive Sciences, Hong Kong, China, ⁴Philips Healthcare, Hong Kong, China

3D multi-slab diffusion-tensor imaging (DTI) can enable high-resolution DTI at submillimeter voxel size. However, the slab boundary artifact and distortion along slab direction can deteriorate the data quality of 3D DTI, thereby limiting its applications. In this work, we proposed a sliding-slab profile encoding (SLIPEN) method to acquire the 3D multi-slab DTI data with sliding-slab technique, and to reconstruct the data free from slab boundary artifact. In addition, off-resonance correction can be incorporated into SLIPEN for producing high-quality artifact-free 3D DTI data.

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