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Abstract #1021

Quantification of T1ρ using magnetic resonance fingerprinting

Brendan Lee Eck1,2, Jeehun Kim2, Mingrui Yang2, and Xiaojuan Li2
1Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, OH, United States, 2Biomedical Engineering, Cleveland Clinic, Cleveland, OH, United States

Quantitative T imaging has been studied for evaluating changes in tissue composition, in particular for detecting early cartilage degeneration in osteoarthritis. Magnetic resonance fingerprinting (MRF) provides a framework for rapid, robust acquisition of quantitative tissue property maps. Simulation experiments using spin-lock prepared MRF with different pulse schedules were conducted to demonstrate the feasibility of quantification of T in addition to T1 and T2. All tested sequences were sensitive to T and produced tissue property maps with major structures of interest. Differing accuracy and precision between sequences suggests opportunities for optimizing MRF for simultaneous T1, T2, and T quantification.

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