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Abstract #1057

Amide Proton Transfer Magnetic Resonance Imaging detecting early Wallerian degeneration of the pyramidal tract after ischemic stroke

Junxin Wang1, Yanwei Miao1, Jiazheng Wang2, Zhiwei Shen2, Bingbing Gao1, Yu Bing1, Yunan Cui1, Ailian Liu1, and Qingwei Song1
1Department of Radiology, the First Affiliated Hospital of Dalian Medical University, Dalian, China, 2Phillips healthcare, China, China

The study aimed to evaluate the significance of amide proton transfer weighted (APTw) imaging in the early diagnosis of pyramidal tract Wallerian degeneration (WD) following cerebral infarction. This study included 25 patients with acute cerebral infarction and 12 healthy adult controls. Our data suggested that the value of APTw was significantly increased on ipsilateral compared to contralateral and the control group in the posterior limb of internal capsule. It proves the feasibility of APTw in early detection of WD.

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