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Abstract #1058

Correlation between APTw changes and regional cerebral oxygen metabolism in ischemic tissue of patients with subacute ischemic stroke

Yuhan Jiang1, Yanwei Miao1, Peipei Chang1, Zhongping Zhang2, Yiwei Che1, Ailian Liu1, Qingwei Song1, and Jiazheng Wang2
1the First Affiliated Hospital of Dalian Medical University, Dalian, China, Dalian, China, 2Philips Healthcare, Beijing, China, Beijing, China

The relationship between APTw and regional cerebral oxygen metabolism levels in the ischemic area is unclear. This study attempts to investigate the mechanism of ischemic tissue pH changes and its influencing factors by measuring the APTw value of ischemic tissue, combined with ASL and SWI. We found that the phase differences of the veins in the infarct (Δφlesion) is positively correlated with APTWmax and APTWmax-min in the ischemic penumbra at PLD1.5.

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