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Abstract #1072

Noninvasive Assessment of Cerebral Collaterals with 3D Multi-inversion Time Arterial Spin Labeling in Ischemic Stroke: Comparison with DSA

Hui Wang1, Chuili Kong2, Quanzhi Feng1, Yi Liu1, Yutian Li1, Jinli Li1, Josef Pfeuffer3, Xianchang Zhang4, and Tong Han1
1Radiology, Tianjin Huanhu Hospital, Tianjin, China, 2Radiology, Liaocheng People’s Hospital, Liaocheng, China, 3Siemens Healthcare, Erlangen, Germany, 4MR Collaboration, Siemens Healthcare Ltd, Beijing, China

This study proposed a new method that can directly visualize and assess the collateral status by post-processing multiphase perfusion-weighted images (PWI) generated by multi-inversion time arterial spin labeling (mTI-ASL), and evaluate its performance by comparison with digital subtraction angiography (DSA) in patients with ischemic stroke. Comparison of the results of 28 patients showed that the collateral status assessed by the 3D mTI-ASL grading system was greatly consistent (kappa coefficient k = 0.854) with DSA. This technique is promising for the noninvasive assessment of the collateral status in stroke patients.

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