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Abstract #1082

3D Free-breathing Cardiac Magnetic Resonance Fingerprinting

Gastao Cruz1, Olivier Jaubert1, Haikun Qi1, Aurelien Bustin1, Giorgia Milotta1, Torben Schneider2, Peter Koken3, Mariya Doneva3, René M. Botnar1, and Claudia Prieto1
1Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2Philips Healthcare, Guildford, United Kingdom, 3Philips Research Hamburg, Hamburg, Germany

2D cardiac Magnetic Resonance Fingerprinting (cMRF) has been proposed for simultaneous and co-registered T1/T2 mapping using ECG-triggering and breath-holding. However, 2D cMRF provides limited coverage of the heart and is sensitive to residual through-plane respiratory motion. Here we propose respiratory motion-compensated 3D cMRF to enable whole-heart myocardial T1/T2 mapping in a single free-breathing scan. Respiratory bellows driven localized autofocus is proposed for beat-to-beat translational motion correction and patch-based low rank MRF reconstruction is employed to minimise residual aliasing. 3D cMRF enabled whole-heart T1/T2 mapping in ~7min scan time with comparable map quality to conventional 2D MOLLI, SASHA and T2-GraSE.

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