Abstract #1082

3D Free-breathing Cardiac Magnetic Resonance Fingerprinting

Gastao Cruz¹, Olivier Jaubert¹, Haikun Qi¹, Aurelien Bustin¹, Giorgia Milotta¹, Torben Schneider², Peter Koken³, Mariya Doneva³, René M. Botnar¹, and Claudia Prieto¹

¹Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ²Philips Healthcare, Guildford, United Kingdom, ³Philips Research Hamburg, Hamburg, Germany

2D cardiac Magnetic Resonance Fingerprinting (cMRF) has been proposed for simultaneous and co-registered T1/T2 mapping using ECG-triggering and breath-holding. However, 2D cMRF provides limited coverage of the heart and is sensitive to residual through-plane respiratory motion. Here we propose respiratory motion-compensated 3D cMRF to enable whole-heart myocardial T1/T2 mapping in a single free-breathing scan. Respiratory bellows driven localized autofocus is proposed for beat-to-beat translational motion correction and patch-based low rank MRF reconstruction is employed to minimise residual aliasing. 3D cMRF enabled whole-heart T1/T2 mapping in ~7min scan time with comparable map quality to conventional 2D MOLLI, SASHA and T2-GraSE.

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